The most dreadful thing a dog owner has to encounter is finding fleas and ticks on their pet’s body. Those tiny little bloodsuckers are a complete nuisance as they not only irritate your furry pal but also cause tick-borne diseases. Fleas and ticks both feed on your dog’s blood and spread harmful infection in the pet’s body. Therefore, it’s highly crucial to administer flea and tick preventive treatment to your Fido.

One of the most recommended and top-selling parasitic treatments for dogs is Frontline Plus, a product of Merial/ Boehringer Ingelheim. To pet parents who are having trouble choosing the right product for their pets, this blog will help you understand how Frontline Plus works and whether it’s suitable for your dog or not. Read on to know everything about Frontline Plus and decide for yourself whether it is right for your pet or not.

History of Frontline Plus

The main ingredient of Frontline Plus is Fipronil, which was formulated between the years 1985 to 1987. Thereafter, it was introduced in the market in the year 1993. Initially, it was marketed as an insecticide to be used for various purposes. Frontline Original only has one ingredient, i.e. Fipronil. On another hand, Frontline Plus has one additional ingredient, S-Methoprene. Frontline Plus was introduced in the year 2000 with the purpose of eliminating fleas as well as its juvenile forms.

What Is Frontline Plus for Dogs?

Frontline Plus for dogs is a top-selling flea and tick preventive treatment. It is a fast-acting topical solution that protects your dog from external parasites and provides long-lasting protection for one full month. The powerful formula starts acting immediately and kills fleas within 12 hours of administration and ticks and biting lice within 48 hours of administration. Moreover, the spot-on solution is developed in such a way that it kills the parasites just upon contact. Frontline Plus kills four types of ticks – American dog tick, brown tick, lone star tick, and deer tick. In addition, it also aids in treating Flea Allergy Dermatitis. Frontline Plus is a vet recommended flea and tick treatment that is highly effective against external parasites.

How It Works?

Frontline Plus is made up of two main ingredients – Fipronil and (s)-methoprene. The main ingredient, Fipronil, eliminates fleas for one full month thus protects the dog from harmful external parasites. (s)-methoprene acts as an insect growth regulator in this treatment. This component disturbs the life cycle of the parasites, thus kills the parasites at all stages. It is doesn’t let flea larvae or flea pupae to develop into adults as it kills them on the spot, hence stopping the flea life cycle altogether. Frontline plus is also safe on pregnant and lactating dogs and dogs and puppies over 8 weeks of age.

Key Benefits

Below are the key benefits of Frontline Plus –

  • Easy to apply topical solution
  • Kills fleas within 12 hours and ticks and biting lice within 48 hours of administration
  • Provides long-lasting protection for up to 4 weeks
  • Helps in treating Flea Allergy Dermatitis (FAD)
  • Waterproof treatment that remains effective even after bathing or swimming
  • Protects the dog from diseases such as Lyme Disease and Rocky Mountain Fever


  • The treatment can be used on dogs only.
  • Store the product at room temperature, away from sunlight.
  • Keep it away from children and other pets.
  • Talk to your vet before using the treatment on aged, convalescing and debilitated pets.
  • Do not use it on puppies below 8 weeks of age.

How is Frontline Plus better than Frontline Top Spot?

Both products are effective in their own way; the only difference between the two treatments is one additional ingredient in Frontline Plus – (s)-methoprene. While Frontline Top Spot only kills and prevents fleas and ticks, Frontline Plus also breaks the life cycle of fleas. Therefore, Frontline Plus is effective on all life stages of fleas.

Frontline Plus is one of the best products in the market and is recommended by many pet parents across the country. Since it’s a topical solution, there’s no fuss of making your dog eat the tablet. It can be easily applied and it will start working immediately. Moreover, the treatment is proven safe for dogs so there’s no risk of adverse effects. Thus, for the betterment of your dog and to prevent him from any kind of parasites and tick-borne diseases, administer Frontline Plus!